Package: xlink 1.0.1
xlink: Genetic Association Models for X-Chromosome SNPS on Continuous, Binary and Survival Outcomes
The expression of X-chromosome undergoes three possible biological processes: X-chromosome inactivation (XCI), escape of the X-chromosome inactivation (XCI-E),and skewed X-chromosome inactivation (XCI-S). To analyze the X-linked genetic association for phenotype such as continuous, binary, and time-to-event outcomes with the actual process unknown, we propose a unified approach of maximizing the likelihood or partial likelihood over all of the potential biological processes. The methods are described in Wei Xu, Meiling Hao (2017) <doi:10.1002/gepi.22097>. And also see Dongxiao Han, Meiling Hao, Lianqiang Qu, Wei Xu (2019) <doi:10.1177/0962280219859037>.
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xlink/json (API)
| # Install 'xlink' in R: |
| install.packages('xlink', repos = c('https://qiuanzhu.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/qiuanzhu/xlink/issues
- Rdata - Simulation data for Genetic association models for X-chromosome SNPS
Last updated 6 years agofrom:068ac3c844. Checks:6 OK, 3 NOTE. Indexed: yes.
| Target | Result | Latest binary |
|---|---|---|
| Doc / Vignettes | OK | Mar 08 2025 |
| R-4.5-win | NOTE | Mar 08 2025 |
| R-4.5-mac | NOTE | Mar 08 2025 |
| R-4.5-linux | NOTE | Mar 08 2025 |
| R-4.4-win | OK | Mar 08 2025 |
| R-4.4-mac | OK | Mar 08 2025 |
| R-4.4-linux | OK | Mar 08 2025 |
| R-4.3-win | OK | Mar 08 2025 |
| R-4.3-mac | OK | Mar 08 2025 |
Exports:select_outputxlink_fit
